PROPOFOL ANTICONVULSANT ACTIVITY IN EXPERIMENTAL EPILEPTIC STATUS
نویسندگان
چکیده
منابع مشابه
Anticonvulsant and antiepileptogenic effects of fluorofelbamate in experimental status epilepticus
PURPOSE To examine the seizure-protective properties of fluorofelbamate, a felbamate analog, on acute and chronic seizures in an experimental model of self-sustaining status epilepticus (SSSE). METHODS SSSE was induced by stimulation of the perforant path for 30 min (PPS) through chronically implanted electrodes in free-running adult male Wistar rats. Fluorofelbamate was injected intravenousl...
متن کاملEpileptic psychoses and anticonvulsant drug treatment.
Forty four consecutive patients with epilepsy and psychoses were studied retrospectively for psychotic episodes associated with changes in antiepileptic drug therapy. Twenty seven patients (61%) developed their first episode of psychosis unrelated to changes in their antiepileptic drug regimen. Twenty three of these patients developed psychoses with temporally unrelated changes in seizure frequ...
متن کاملAn experimental evaluation of anticonvulsant activity of Vitex-negundo.
Maximal electroshock seizures (MES) in albino rats and pentylenetetarazole (PTZ) induced seizures in albino mice were used to study anticonvulsant activity of Vitex-negundo leaf extract. The ethanolic leaf extract of Vitex-negundo was administered orally in graded doses (250, 500 and 1000 mg/kg p.o) in both the experimental models and the effects were compared with diphenylhydantoin in MES meth...
متن کاملTiming of Anticonvulsant Administration in Status Epilepticus.
Investigators from the Pediatric Status Epilepticus Research Group studied the time elapsed from onset of pediatric convulsive status epilepticus (SE) to administration of antiepileptic drugs (AED).
متن کاملIn silico Screening and Evaluation of the Anticonvulsant Activity of Docosahexaenoic Acid-Like Molecules in Experimental Models of Seizures
Background: Resistance to antiepileptic drugs as well as intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid (DHA), make it as a good candidate for designing and development of the new anticonvulsant medications. Methods: Ten DHA-based...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1992
ISSN: 0007-0912
DOI: 10.1093/bja/69.2.177